Studies have found a strong association between vitiligo and various autoimmune diseases like thyroid cancer, Addison’s disease, lupus, and others. However, the most common conception of vitiligo is the loss of pigmentation. Treating vitiligo in the early stages is vital due to its possibility of leading to other diseases. In this post, I will write about Ginkgo Biloba For Vitiligo and will give some Callumae Reviews.
Ginkgo Biloba For Vitiligo – A Complete Guide
Ginkgo Biloba effectively stalls the progression of vitiligo and speeds up the process of repigmentation in patients. Ginkgo Biloba has antioxidant properties which impact vitiligo’s oxidative stress mechanisms. Along with its effect on vitiligo, Ginkgo Biloba reportedly improves dementia-associated symptoms like anxiety, improves the patient’s efficiency of sleep, and reduces the number of interrupted awakenings. 
There are no guidelines regarding the maximum dosage of Ginkgo Biloba per day. Some manufacturers recommend 120 mg. of standardized Ginkgo Biloba to be taken with the meal twice a day, continuously for at least 12 weeks. Given that it helps modulate the immune system, Ginkgo Biloba has shown some degree of effectiveness in treating vitiligo. The effectiveness of Ginkgo Biloba has been reiterated in clinical tests. In a double-blind, randomized trial conducted in India, it was found that a daily intake of 120 mg. of Ginkgo Biloba in three courses a day for six months curtailed the spread of vitiligo in 20 out of the 25 active group participants and initiated marked repigmentation of at least 75% in around 10 of these 20 participants. EGb 761, an extract of Ginkgo Biloba, significantly curtailed a rise in systolic and diastolic blood pressure induced by stress. Another study showed an intake of 60 mg. of Ginkgo Biloba significantly improved the vitiligo measures in the Vitiligo Area Scoring Index (VASI). However, Ginkgo Biloba is not free from side effects. Though it is to be “likely safe” to take a leaf extract of the Ginkgo Biloba orally, there could be some minor side-effects like allergic skin reactions, headaches, and stomachaches, among others. The leaf extract is “possibly safe” when used intravenously with dipyridamole for up to 30 days. Severe allergic skin reactions and mucous membrane irritations can be caused by an oral intake of the Ginkgo fruit and pulp. Gingko is known to turn the blood thin and reduce the time for clotting. There have been people who had excessive bleeding from the eye, lungs, brain, and even in post-surgery scenarios. The roasted seed of the Gingko is classified as “possibly unsafe” for oral intake. Daily intake of more than ten seeds can cause seizures, loss of consciousness, breathing difficulty, and a weak pulse, among others. Eating fresh Ginkgo seeds is “likely unsafe” as it is poisonous and can cause seizures and even death. Patients using anticoagulants have to exercise caution because Ginkgo Biloba can augment the effects of the anticoagulant intake. The doctor’s advice must be taken by patients using aspirin, nicardipine, and valproate before using Ginkgo Biloba. Patients who are allergic to alkyl-phenol-producing plants like poison ivy and cashew, among others, have to be cautious while consuming Ginkgo Biloba due to the possibility of an allergic reaction. Patients have to carefully read the labels before purchasing them because Ginkgo seeds contain a higher neurotoxin concentration than Ginkgo leaves.
Ginkgo Biloba Paste For Vitiligo
The Ginkgo Biloba paste, an ancient traditional Chinese medicine famous worldwide for its medicinal properties, helps maintain the skin’s overall health and color. Li Shizhen, a 15th-century herbalist from China, wrote a book called Ben Cao Gang Mu, which translates to “Compendium of Materia Medica.” According to Li, the Ginkgo Biloba seeds have to be grounded into a paste mixed either with rice wine or rapeseed oil, and the final paste is applied to the affected parts. Though the knowledge is ancient, it was reaffirmed by recent research. The University of Maryland School of Pharmacy in Baltimore conducted medical research that showed that applying this paste on the affected part of the skin treats various skin diseases. A paste made from Ginkgo Biloba and water helps significantly cut down the white patches on the skin. The paste has to be applied to the affected parts and left for about 30 minutes, after which it should be rinsed with warm water. Doing this regularly facilitates repigmentation in the affected area and gives the skin its natural color back.
Callumae Review – UPDATED 2021
The reviews for Callumae have been mixed. Some users have found Callumae efficient and delivering results and have given it a five-star rating. According to some users, the product does not do its job, and they are thoroughly unimpressed with the product. One user mentions that the white patch on the skin turns red instead of regenerating the pigments and advises people with dark skin not to try the product as the redness might be distinctly visible so he prefers to use Aloe Vera to treat his Vitiligo. 
Another user mentions that though Callumae did nothing to improve his vitiligo, it helped with his leg pain, totally unrelated to vitiligo. However, the user reminds the customers that using Callumae changes the color and odor of the urine. A user had tried four bottles of Callumae to no avail and says that his taste buds feel odd after taking the capsules. The sellers, however, have given high ratings-4.8 out of 5 stars for the product.
Callumae Capsules Price
Callumae capsules are sold in the US for $47. It is sold in India between ₹9000 and ₹ 12000, including customs duty in India.
Callumae Ingredients
Callumae contains Vitamin B6 in pyridoxine HCL, folic acid, Vitamin B12 in the form of cyanocobalamin, picrorhiza, leaf extracts from Ginkgo Biloba, l-phenylalanine, and alpha-lipoic acid. Other ingredients in Callumae include rice powder, magnesium stearate, and hypromellose in vegetarian capsules free of gelatine and animal by-products. It is manufactured in Anaheim, California, and is a product of Progressive Health Nutraceuticals, which has been working since 2004 to address various health concerns. Callumae is meant to be used along with light therapy like natural sunlight therapy for better results. Clinical research shows that l-phenylalanine is effective for both children and adults with vitiligo combined with light therapy. Clinical trials have shown that 12 months of treating vitiligo with Callumae and light therapy have led to at least a 50% repigmentation in the patients’ face, back, arms, and legs. Intake of Vitamin B12, folate, and Vitamin C along with UVB (Ultraviolet B) therapy stalls the depigmentation process and initiates repigmentation after 6 to 8 weeks. Callumae can be complimented with any existing therapy like UVA, PUVA, and UVB, irrespective of age, the extent of the spread of vitiligo, and the treatment used. Callumae uses a blend of botanicals for immunological functions and skin health processes. Picrohiza is used in Ayurveda for treating immune dysfunctions. It also treats oxidative stress with the presence of antioxidants like lipoic acid and Gingko Biloba.
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